Overview

Major Brands

Ozempic, Wegovy, and Rybelsus

How it Works

• GLP-1 receptor agonist (mimics the hormone glucagon-like peptide-1).

• Slows gastric emptying, reduces appetite, and increases insulin release in response to glucose.

Effects

• Proven strong weight-loss and glucose-control benefits.

• Average weight loss (Wegovy trials): ~15% of body weight over ~68 weeks.